Human Reproduction, Infertility, and Family Planning
Brings together the expertise of clinicians and researchers working in reproductive health. The research portfolio spans from molecular investigation into the health of oocytes, sperm and embryos to clinical research of common gynecological conditions, such as endometrial and polycystic ovary syndrome. The research is focusing on epigenetics on reproduction (DNA methylation and microRNAs expression), new approach on pre-implantation genetic testing for aneuploidy (PGT-A) using non-invasive methods and also mitochondrial DNA as a biomarker for oocytes and embryos quality.
Ongoing Research
- Korelasi Kadar Androgen Cairan Folikel dan ekspresi reseptor FSH Sel Granulosa pada Perespon Buruk.
- Korelasi kadar AMH Cairan Folikel dengan Rasio Ekspresi BAX/BCL-2 Sel Granulosa pada Pasien Sindroma Ovarian Polikistik (SOPK).
- Studi Profil mRNA Gen GDF9 dan BMP15 pada Sel Granulosa dalam Meramal Kualitas Oosit pada Pasien yang Menjalani Pragram Bayi Tabung.
- Profil Metilasi Gen-gen yang Terlibat dalam Metabolisme Insulin dan Androgen pada Pasien PCOS.
- Pengaruh metilasi DNA gen PGR-A dan PGR-B pada jaringan endometriosis.
- Studi Terhadap Viabilitas Korteks Ovarium Pasca Vitrifikasi dan Transplantasi Pada Macaca fascicularis Sebagai Upaya Pengembangan Pusat Preservasi Fungsi Reproduksi Pada Penderita Kanker Pasca Kemoradiasi.
- Evaluasi Penggunaan Bahan Medis Habis Pakai dengan Sistem Paket dan Non Paket sebagai Upaya Efisiensi Biaya di RSCM.
- Pengaruh condition medium pada kultur sel granulos.
- Kegunaan aplikasi IKO dalam menentukan usia biologis serta dampaknya terhadap pemilihan teknologi reproduksi di l ingkungan RSCM, Jakarta, Indonesia.
- Perubahan Luteinizing Hormone (LH), Sluble Leptin Receptor (Sob-R), Leptin, Estradiol, dan Keluhan Vasomotor sebagai Faktor Peramal Hendaya Kognitif Nir-Demensia pada Perempuan Menopause.
- CD107A untuk Identifikasi Aktivasi Sel Natural Killer pada Pasien Endometriosis.
- Next Generation Sequencing : Peningkatan Akses dan Akurasi Penapisan Kelainan Genetik Pra-Implantasi.
- Program Ipteks Bagi Masyarakat.
- Studi Viabilitas Korteks Ovarium dan Folikel Pre-Antral Manusia dan Maturasi Oosit Pasca Vitrifikasi di Pusat Preservasi Fertilitas Indonesia.
Publication
| No | Title | Type of Journal | Year | Authors |
|---|---|---|---|---|
| 1 | Mechanism of elevated LH/FSH ratio in lean PCOS revisited: a path analysisMechanism of elevated LH/FSH ratio in lean PCOS revisited: a path analysis | Scientific Reports | 2024 | Gita Pratama, Budi Wiweko, Asmarinah , Indah S. Widyahening, Trinovita Andraini, Hartanto Bayuaji, Andon Hestiantoro |
| 2 | Associations of HSD17B1 Gene Expression with its DNA Methylation and Estradiol Level in Polycystic Ovary Syndrome Indonesian Patients | OnLine Journal of Biological Sciences | 2024 | Rina Puspita, Andon Hestiantoro, Rina Agustina, Nining Handayani, Batara Immanuel Sirait, Arie Adrianus Polim, Asmarinah |
| 3 | Fertility education on Instagram:advertisements vs. educational content analysis for posts in Bahasa (Indonesian language) | Annals of Medicine & Surgery | 2024 | Achmad K Harzif, PhD, Berli Kusuma,Nafi’atul Ummah, Aisyah R Puspawardani, Putri Nurbaeti, Budi Wiweko |
| 4 | Knowledge and Behavior in Human Immunodeficiency Viruses and Reproductive Health of Human Immunodeficiency Viruses-infected Serodiscordant Couples in the Capital City of Indonesia | International Journal of Infertility and Fetal Medicine | 2024 | Novy Yanthi, Achmad K Harzif, Mila Maidarti, Evy Yunihastuti, Gita Pratama |
| 5 | Knowledge, attitudes, and practices regarding Covid-19 and their relationship with Covid-19 booster vaccination status among women with infertility | Asian Pacific Journal of Reproduction | 2024 | Gita Pratama, Mila Maidarti, Kanadi Sumapradja, Achmad Kemal Harzif, Natasha Talya, Kevin Ezekia, Irfan Arieqal Hatta Ampri |
| 6 | Association of hirsutism and anthropometric profiles with sexual dysfunction and anxiety levels in infertile Indonesian women with polycystic ovarian syndrome | Middle East Fertility Society Journal | 2024 | Deniswari Rahayu, Alfa Putri Meutia, Tyas Priyatini, Ni Made Desy Suratih, Mila Maidarti, Achmad Kemal Harzif, R. Muharam, Gita Pratama |
| 7 | Fertility education on Instagram: advertisements vs. educational content analysis for posts in Bahasa (Indonesian language) | Annals of Medicine & Surgery | 2024 | Achmad K Harzif, Berli Kusuma, Nafi’atul Ummah, Aisyah R Puspawardani, Putri Nurbaeti, Budi Wiweko |
| 8 | Embryo response to aneuploidy through self-correction mechanism: a literature review | Middle East Fertility Society Journal | 2024 | Achmad Kemal Harzif, Azizah Fitriayu Andyra, Atikah Sayogo, Nafi’atul Ummah, Aisyah Retno Puspawardani, Putri Nurbaeti, Budi Wiweko |
| 9 | Sperm Quality and its Association with Embryonic Aneuploidy Outcomes in Preimplantation Genetic Testing for Aneuploidies (PGT-A) | Fertility & Reproduction | 2024 | Sarah Susanto, Tiara Berliana Azzahra, Pritta Ameilia Iffanolida, Kresna Mutia, Oki Riayati, Budi Wiweko |
| No | Title | Type of Journal | Year | Authors |
|---|---|---|---|---|
| 1 | microRNAs as A Biomarker to Predict Embryo Quality Assessment in In Vitro Fertilization | International Journal of Fertility & Sterility | 2023 | Kresna Mutia, Budi Wiweko, Abinawanto, Astari Dwiranti, Anom Bowolaksono |
| 2 | Down-Regulation of miR-93 Negatively Down-Regulation of miR-93 Negatively Correlates with Overexpression of VEGFA and MMP3 in Endometriosis: A Cross-Sectional Study | International Journal of Fertility & Sterility | 2023 | R. Muharam, Ririn Rahmala febri, Kresna Mutia, Pritta Ameilia Iffanolida, Mila Maidarti, Budi Wiweko, Andon Hestiantoro |
| 3 | Severe chronic pelvic pain due to cystic degeneration of subserosal uterine fibroid with type 2 diabetes and obesity: Serial case report | Obstetrics and Gynecology Science | 2023 | Mila Maidarti, Beta Andewi Resti Anngraheny, Sarah Safira Umarhanies, Prini Diandara Garinasih, Achmad Kemal Harzif, Octaviyana Nadia Nitasari Simatupang |
| 4 | Twelve Hours Post-Injection Serum Human Chorionic Gonadotropin and Body Mass Index Predicts In Vitro Fertilization Oocyte Maturation Rate: A Cross-Sectional Study | Bali Medical Journal | 2023 | Batara Sirait, Budi Wiweko, R. Muharam, Ahmad Aulia Jusuf, Ichramsjah A. Rachman, Arief Boediono |
| 5 | Sequencing Analysis of Anti Mullerian Hormone in Polycystic Ovarian Syndrome and Primary Ovarian Insufficiency | Bali Medical Journal | 2023 | Budi Ermanto, Fadilah, Anom Bowolaksono, Asmarinah, Tono Djuwantono, Aria Kekalih, mila Maidarti, Wisnu Ananta Kusuma, Budi Wiweko |
| 6 | Factors Attributed to Depressive Symptoms in Women Coping with Infertility During the Pandemic of COVID-19 | Bali Medical Journal | 2023 | Mila Maidarti, Emily Bailie, Aprilia Siregar, Prini Diandara Garinasih, Vita Silvana, Achmad Kemal Harzif, Gita Pratama, Kanadi Sumapraja, R. Muharam, Andon Hestiantoro, Budi Wiweko |
| 7 | Characteristics of Embryo Mosaicism Detected Using Next-Generation Sequencing PGT-A | Fertility & Reproduction | 2023 | Muhammad Ikhsan, Pritta Ameilia Iffanolida, Ms Kresna Mutia, Raden Muharam, Budi Wiweko, Kanadi Sumapraja, Gita Pratama, Achmad Kemal Harzif, Mila Maidarti, Vita Silvana, Andon Hestiantoro |
| 8 | miR-135b Expression Correlated with Aneuploidy in Trophectoderm from IVF Patients: An Approach to NIR-Invasive Screening for Embryo Quality Assessment | Fertility & Reproduction | 2023 | Kresna Mutia, Anom Bowolaksono, Ririn Rahmala Febri, Pritta Ameilia Iffanolida, Gita Pratama, Achmad Kemal Harzif, Mila Maidarti, Kanadi Sumapraja, R. Muharam, Andon Hestiantoro, Budi Wiweko |
| 9 | Result of Non-Invasive Preimplantation Genetic Testing for Aneuploidy in Different Culture Medium Condition | Fertility & Reproduction | 2023 | Pritta Ameilia Iffanolida, Dr Achmad Kemal Harzif, Kresna Mutia, Ririn Rahmala Febri, Deka Putri Gunarwati4, Mila Maidarti, Budi Wiweko, Andon Hestiantoro |
| 10 | The Correlation Between Insulin Resistance with Serum Androgens Levels in Lean Women With and Without PCOS | Fertility & Reproduction | 2023 | Oki Riayati, Gita Pratama, R Muharam, Andon Hestiantoro, Budi Wiweko, Naylah Muna, Irfan Arieqal Hatta Ampri, Kevin Ezekia, Niken Rivie Kenyia, Pritta Ameilia Iffanolida, Kresna Mutia, Ririn Rahmala |
| 11 | Relationship Between Level Expression of miRNA-191 and miRNA-548c-3p in Embryo Culture Medium and Embryo Chromosomal Status | Fertility & Reproduction | 2023 | Riyan Hari Kurniawan, Raden Muharam, Dr. Indah Suci Widyahening, Pritta Ameilia Iffanolida, Budi Wiweko |
| 12 | Ultra-Long Protocol During IVF Outcome in Infertile Women with Endometriosis | Fertility & Reproduction | 2023 | Dafi Yulinda, Louis Regan, Fahreza Akbar Siregar, Axel Jovito, Budi Wiweko |
| 13 | Result of Non-Invasive Preimplantation Genetic Testing for Aneuploidy in Different Culture Medium Condition | Fertility & Reproduction | 2023 | Pritta Ameilia Iffanolida, Achmad Kemal Harzif, Kresna Mutia, Ririn Rahmala Febri, Deka Putri Gunarwati, Mila Maidarti, Budi Wiweko, Andon Hestiantoro |
| 14 | Dual Triggers of Ovidrel and Buserelin Improves the Outcome of In Vitro Fertilization in Yasmin Fertility Clinic | Fertility & Reproduction | 2023 | Axel Jovito, Fahreza Akbar Siregar, Dafi Yulinda, Louis Regan, Budi Wiweko |
| 15 | The Use of Follitropin-Delta in Indonesia: Current Evidence and Development | Fertility & Reproduction | 2023 | Fahreza Akbar Siregar, Dr. Axel Jovito, Dafi Yulinda, Louis Regan,Budi Wiweko |
| 16 | Comparison of In Vitro Fertilization in Couples with HIV Infection with Negative Viral Load Versus Non-Infected Couples: A Case-Control Study | Fertility & Reproduction | 2023 | R Muharam Natadisastra, Budi Wiweko, Gita Pratama, Tita Yuningsih, Aswan Bagastoro, Anindita Abigail, Mila Maidarti, Achmad Kemal Harzif, Kanadi Sumapraja, Andon Hestiantoro |
| 17 | Comparison of In Vitro Fertilization in Couples with HIV Infection with Negative Viral Load Versus Non-Infected Couples: A Case-Control Study | Fertility & Reproduction | 2023 | R Muharam Natadisastra, Budi Wiweko, Gita Pratama, Tita Yuningsih, Aswan Bagastoro, Anindita Abigail, Mila Maidarti, Achmad Kemal Harzif, Kanadi Sumapraja, Andon Hestiantoro |
| 18 | The Relationship Between Maternal Age and the Chromosomal Status of the Embryo | Fertility & Reproduction | 2023 | Riyan Hari Kurniawan, Raden Muharam, Indah Suci Widyahenin, Pritta Ameilia Iffanolida, Budi Wiweko |
| 19 | miR-135b Expression Correlatedwith Aneuploidy in Trophectodermfrom IVF Patients: An Approach toNIR-Invasive Screening for EmbryoQuality Assessment | Fertility & Reproduction | 2023 | Kresna Mutia, Anom Bowolaksono, Ririn Rahmala Febri, Pritta Ameilia Iffanolida,Gita Pratama, Achmad Kemal Harzif, Mila Maidarti, Kanadi Sumapraja, R. Muharam, Andon Hestiantoro, Budi Wiweko |
| 20 | Characteristics of Embryo Mosaicism Detected Using Next-Generation Sequencing PGT-A | Fertility & Reproduction | 2023 | Muhammad Ikhsan, Pritta Ameilia Iffanolida, Kresna Mutia, Raden Muharam, Budi Wiweko, Kanadi Sumapraja, Gita Pratama, Achmad Kemal Harzif, Mila Maidarti, Vita Silvana, Andon Hestiantoro |
| 21 | Comparison of In Vitro Fertilization in Couples with HIV Infection with Negative Viral Load Versus Non-Infected Couples: A Case-Control Study | Fertility & Reproduction | 2023 | R Muharam Natadisastra, Budi Wiweko, Gita Pratama, Tita Yuningsih, Aswan Bagastoro, Anindita Abigail, Mila Maidarti, Achmad Kemal Harzif, Kanadi Sumapraja, Andon Hestiantoro |
| No | Title | Type of Journal | Year | Authors |
|---|---|---|---|---|
| 1 | Vitamin B3 (niacin), B6 , C, and iron intake are associated with the free androgen index, especially in normoandrogenic polycystic ovary syndrome | Journal of the Turkish German Gynecology Association | 2022 | Andon Hestiantoro, Brilliant Putri Kusuma Astuti, Ericko Ongko Joyo, Ririn Rahmala Febri, Vita Silvana, Raden Muharam |
| 2 | Down-regulation of miR-93 negatively correlates with overexpression of VEGFA and MMP3 in endometriosis | International Journal of Fertility and Sterility | 2022 | International Journal of Fertility and Sterility |
| 3 | Inflammatory markers in lean Polycystic Ovary Syndrome subjects are not associated with the spectrum of dyslipidemia | Journal of Obstetrics & Gynecology Science | 2022 | Elisia Atnil , Andon Hestiantoro, Oki Riayati, Ririn Rahmala Febri, Naylah Muna |
| 4 | Potential Use of Immature Oocyte to Improve Fertility Preservation Outcome: A Narrative Review | Journal of Human Reproductive Sciences | 2022 | Batara Sirait, Ahmad Aulia Jusuf , Budi Wiweko , Nining Handayani, Daniel Abidin Aubry, R Muharam |
| 5 | Embryo grading after in vitro fertilization using yolo | Lontar Komputer | 2022 | Dewi Ananta Hakim, Ade Jamal, Anto Satriyo Nugroho, Ali Akbar Septiandri, BudiWiweko |
| 6 | Mitochondrial DNA copy number in cumulus granulosa cells as a predictor for embryo morphokinetics and chromosome status Mitochondrial DNA copy number in cumulus granulosa cells as a predictor for embryo morphokinetics and chromosome status | Systems Biology in Reproductive Medicine | 2022 | Pitra Rahmawati, Budi Wiweko, Arief Boediono |
| 7 | Anti-Müllerian hormone independently affect mtDNA copy number in human granulosa cells | Journal of Ovarian Research | 2022 | Anom Bowolaksono, Ayu Mulia Sundari, Muhammad Fauzi, Mila Maidarti, Budi Wiweko, Kresna Mutia, Pritta Ameilia Iffanolida, Ririn Rahmala Febri, Astari Dwiranti, Hiroaki Funahashi |
| 8 | The Correlation of Chronological Age and Micro Ribonucleic Acid-135b Expression in Spent Culture Media of In vitro Fertilisation Patient | Journal of Human Reproductive Sciences | 2022 | Tiara Berliana Azzahra , Ririn Rahmala Febri , Pritta Ameilia Iffanolida , Kresna Mutia, Budi Wiweko |
| 9 | Potential Use of Immature Oocyte to Improve Fertility Preservation Outcome: A Narrative Review | Journal of Human Reproductive Sciences | 2022 | Batara Sirait, Ahmad Aulia Jusuf , Budi Wiweko , Nining Handayani, Daniel Abidin Aubry , R Muharam |
| 10 | Vitamin B3 (niacin), B6, C, and iron intake are associated with the free androgen index, especially in normoandrogenic polycystic ovary syndrome | Journal Of The Turkish-German Gynecological Association | 2022 | Andon Brilliant, Brilliant Putri Kusuma Astuti, Ericko Ongko Joyo, Ririn Rahmala Febri, Vita Silvana, Raden Muharam |
| 11 | The Effect of Anti-VDAC3 Recombinant Antibody on the Motility, Viability, and Membrane Integrity of Ejaculated Human Sperm | International Journal of Pharma Medicine and Biological Sciences | 2022 | Laila Chuvita, Nurul Hikmawati, Silvia Werdhy Lestari, Andon Hestiantoro, Asmarinah |
| 12 | Effect of conditioned medium of umbilical cord-derived mesenchymal stem cells as a culture medium for human granulosa cells: An experimental study | International Journal of Reproductive BioMedicine | 2022 | Kanadi Sumapraja, Andon Hestiantoro, Isabella Kurnia Liem, Arief Boediono, Teuku Z Jacoeb |
| 13 | Inflammatory markers in lean Polycystic Ovary Syndrome subjects are not associated with the spectrum of dyslipidemia | Majalah Obstetri & Ginekologi | 2022 | Elisia Atnil, Andon Hestiantoro, Oki Riayati, Ririn Rahmala Febri, Naylah Muna |
| No | Title | Type of Journal | Year | Authors |
|---|---|---|---|---|
| 1 | The Essence of Telemedicine for Bridging the Gap in Health Services | Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal) | 2021 | Budi Wiweko, Sarah Chairani Zakirah, Atha Luthfi |
| 2 | Carrier RNA (cRNA) Enhances dsDNA Recovery Extracted from Small Volume Spent Embryo Culture Medium | International Journal on Advanced Science Engineering and Information Technology | 2021 | Ayu Mulia Sundari, Pritta Ameilia Iffanolida, Kresna Mutia, Naylah Muna, Eliza Mansyur, Andon Hestiantoro, Budi Wiweko, Muhammad Fauzia, Anom Bowolaksono |
| 3 | Oocyte Competence Biomarkers Associated With Oocyte Maturation: A Review | Frontiers in Cell and Developmental Biology | 2021 | Batara Sirait, Budi Wiweko, Ahmad Aulia Jusuf, Dein Iftitah, R. Muharam |
| 4 | Anti-Müllerian Hormone Levels as Predictor of In Vitro Fertilization Outcomes | eJournal Kedokteran Indonesia | 2021 | Mila Maidarti, Prini D. Garinasih, Aprilia A. Siregar, Gita Pratama, Achmad K. Harzif, Kanadi Sumapraja, Budi Wiweko |
| 5 | COVID-19 Pandemic Impacts Decision-Making and Psychosocial Behavior in Women Seeking Fertility Treatment in APAC—an ASPIRE Patient Experience Report | Fertility & Reproduction | 2021 | Budi Wiweko, Tuong M. Ho, Atsushi Tanaka, Vanessa Raggio, Jung-Ryeol Lee, Milind Patil, Carina Chi-Wai Chan, Teraporn Wutayavanich, Feiyang Diao, Suresh Nair, Rudie Frederick Mendiola |
| 6 | Increased Levels of CD107a and Intracellular Cytokines in IL-2 Stimulated PBMCs from Endometriosis Patients | International Journal of Inflammation | 2021 | R. Muharam, Ririn Rahmala Febri, Kevin Ardito Prabowo, Arleni Bustami, Indra G. Mansur |
| No | Title | Type of Journal | Year | Authors |
|---|---|---|---|---|
| 1 | Correlation of anti-Mullerian hormone levels with metabolic syndrome events in polycystic ovary syndrome: A cross-sectional study | International Journal of Reproductive BioMedicine | 2020 | Wiweko B, Handayani LK, Harzif AK, Pratama G, Muharam R, Hestiantoro A, Sumapraja K. |
| 2 | CYP19A1 gene expression in patients with polycystic ovarian syndrome | Journal of Human Reproductive Sciences | 2020 | Panghiyangani R, Soeharso P, Andrijono, Suryandari DA, Wiweko B, Kurniati M, Pujianto DA |
| 3 | Analysis of mrna expression and dna methylation level of rac1 gene encoding focal adhesion molecule in endometrial and peritoneal endometriosis. | Asia-Pacific Journal of Molecular Biology and Biotechnology | 2020 | Deraya, I. E., Hestiantoro, A., Muharam, R., Marwali, M. L., As’adi, A. S., Darmawi, Harzif, A. K., Pratama, G., Ocktariyana, Zahrah, A. & Asmarinah |
| 4 | Human Blastocyst Classification after In Vitro Fertilization Using Deep Learning | International Conference of Advance Informatics: Concepts, Theory, and Applications (ICAICTA). | 2020 | Ali Akbar Septiandri; Ade Jamal; Pritta Ameilia Iffanolida; Oki Riayati; Budi Wiweko |
| 5 | Carrier RNA (cRNA) Enhances dsDNA Recovery Extracted from Small Volume Spent Embryo Culture Medium | International Journal on Advanced Science, Engineering, Information, and Technology | 2020 | Sundari AM, Iffanolida PA, Mutia K, Muna N, Mansyur E, Hestiantoro A, Wiweko B, Fauzi M, and Bowolaksono A. |
| 6 | MicroRNA 135b Expression in spent Blastocyst Media Culture and Its Association with Aneuploidy in IVF Patients | Preliminary results were presented at Virtual Conference The 6th International Symposium on Current Progress in Mathematics and Science | 2020 | Tiara Berliana Azzahra, Ririn Rahmala Febri, Pritta Ameilia Iffanolida, Kresna Mutia, Budi Wiweko |
| 7 | The relationship between GDF-9 and BMP-15 serum and follicular fluid and the quality of oocytes in women who undergo an IVF cycle | International Journal of Applied Pharmaceutics | 2020 | Arifin, Z., Sumapradja, K., Anggraeni, U., Muna, N., & Wiweko, B. |
| 8 | Analysis of factors associated with ovarian reserve in a group of poor responders to in vitro fertilization: A cross-sectional study | International Journal of Reproductive BioMedicine | 2020 | Wiweko B, Afdi Q F, Harzif A K, Pratama G, Sumapraja K, Muharam R, et al |
| 9 | Analysis of factors associated with ovarian reserve in a group of poor responders to in vitro fertilization: A cross-sectional study | International Journal of Reproductive BioMedicine | 2020 | Wiweko B, Afdi QF, Harzif AK, Pratama G, Sumapradja K, Muharam R, Hestiantoro A, Zakirah SC. |
| 10 | In vitro Activation of Mouse Oocytes through Intracellular Ca2+ Regulation. | Journal of Human Reproductive Sciences | 2020 | Handayani N, Wiweko B, Zakirah SC, Boediono A. |
| 11 | Suppressing HOXA-10 Gene Expression by MicroRNA 135b During the Window of Implantation in Infertile Women | Journal of Reproduction & Infertility | 2020 | Riyanti A, Febri RR, Zakirah SC, Harzif AK, Rajuddin R, Muharam R, Asmarinah A, Wiweko B. |
| 12 | Impact of Serum Human Chorionic Gonadotropin and Luteinizing Hormone Receptor Expression to Oocyte Maturation Rate: A Study of Controlled Ovarian Stimulation | Journal of Human Reproductive Sciences | 2020 | Hilwah Nora , Budi Wiweko, R Muharam, Rajuddin, Grace Wangge, Andon Hestiantoro, Gita Pratama, Achmad Kemal Harzif, Sarah Chairani Zakirah |
| No | Title | Type of Journal | Year | Authors |
|---|---|---|---|---|
| 1 | BMP15 mRNA profile in granulosa cells from endometriosis patients undergoing in vitro fertilization | Journal of Physics: Conference Series | 2019 | B Wiweko, P A Iffanolida, Z Rectifa , N Muna, K Mutia, R R Febri, S Rahmawati, O Riayati and A Hestiantoro |
| 2 | Dysregulation of Kisspeptin and Leptin, as Anorexigenic Agents, Plays Role in the Development of Obesity in Postmenopausal Women | International Journal of Endocrinology | 2019 | Brilliant P. K. Astuti,Raden Muharam, Gita Pratama,Fiastuti Witjaksono, and Budi Wiweko |
| 3 | Community Perspectives about Reproductive Health and JAKPROS Smart Mobile Application | IOP Conference Series: Earth and Environmental Science | 2019 | Budi Wiweko, M. Luky Satria, Kresna Mutia, Pritta Ameilia Iffanolida, Achmad Kemal Harzif, Gita Pratama, R. Muharam, Andon Hestiantoro |
| 4 | Correlation between luteinizing hormone receptor gene expression in human granulosa cells with oocyte quality in poor responder patients undergoing in vitro fertilization: A cross-sectional study | F1000Research | 2019 | Budi Wiweko, Yassin Yanuar Mohammad, Naylah Muna, Kresna Mutia, Julianto Witjaksono, Nuri Purwito Adi, Mila Maidarti, Achmad Kemal Harzif, Gita Pratama, Kanadi Sumapraja, R. Muharam, Andon Hestiantoro |
| 5 | A high dose of total recombinant FSH suppresses granulosa cell apoptosis and maintains oocyte quality in endometriosis: A cross-sectional study | F1000Research | 2019 | Budi Wiweko, Yassin Yanuar Mohammad, Naylah Muna, Kresna Mutia, Julianto Witjaksono, Nuri Purwito Adi, Mila Maidarti, Achmad Kemal Harzif, Gita Pratama, Kanadi Sumapraja, R. Muharam, Andon Hestiantoro |
| 6 | Electroacupuncture Enhances Number of Mature Oocytes and Fertility Rates for In Vitro Fertilization | Medical Acupuncture | 2019 | Ayu Cintani Kusuma, Nadia Oktari, Hasan Mihardja, Adiningsih Srilestari, Christina L. Simadibrata, Andon Hestiantoro, Budi Wiweko, Naylah Muna |
| 7 | DNA methylation of P2X3 receptor gene encoded pain marker protein in endometriosis | Journal of Physics Conference Series | 2019 | Ocktariyana, Hestiantoro A, Rahmala, Asmarinah |
| 8 | The Frequency of Chromosomal Euploidy Among 3PN Embryos | Journal of Reproduction and Infertility | 2019 | Kresna Mutia , Budi Wiweko, Pritta Ameilia Iffanolida, Ririn Rahmala Febri, Naylah Muna, Oki Riayati, Shanty Olivia Jasirwan, Tita Yuningsih, Eliza Mansyur, Andon Hestiantoro |
| 9 | Cito-compability analysis of mesenchymal stem cells in platelet rich fibrin matrix (PRFM) for tissue regeneration | AIP Conference Proceedings | 2019 | Gita Pratama, Budi Wiweko, Normalina Sandora, Evanti Kusumawardhani, Deniswari Rahayu, Kamila Puspita |
| 10 | Cutting Edge of Reproductive Medicine | Fertility & Reproduction | 2019 | Budi Wiweko |
| No | Title | Type of Journal | Year | Authors |
|---|---|---|---|---|
| 1 | Histoanalysis and sterility assay of fresh human amniotic membrane for use in urogynecology | Journal of Physics: Conference Series | 2018 | Normalina Sandora, Gita Pratama, Selvi Rahmawati, D Rahayu, Budi Wiweko |
| 2 | Jakpros: Reproductive Health Education Application for Pregnant Women | ICACSIS | 2018 | Budi Wiweko, Aida Riyanti, Shanty Olivia, Muhammad Priangga, Vita Silvana, Ilonna Putri Pertiwi, Yohanes Satrya Wibawa, Ririn Rahmala Febri, Anggi Lewis Reso Putro, Prince Gusti Agung, Andon Hestiantoro, Raden Muharram, Achmad Kemal Harzif, Gita Pratama |
| 3 | Study of GDF9 and BMP15 mRNA profiles in granulosa cells to predict oocyte quality in endometriosis patients undergoing in vitro fertilization | Journal of Physics: Conference Series | 2018 | N Muna, B Wiweko, Z Rectifa, K Mutia, O Riayati, P A Iffanolida, R Muharam, A Hestiantoro |
| 4 | DNA methylation analysis of anti-mullerian hormone gene in ovarian granulosa cells in PCOS patients | Journal of Physics: Conference Series | 2018 | A D Wijaya, R R Febri, Desmawati, A Hestiantoro, Asmarinah |
| 5 | Correlation between androgen levels in follicular fluid and granulose cell FSHR expression in poor responder women | Journal of Physics: Conference Series | 2018 | B Wiweko, N M D Suratih, N Hanifah, A M Sholilah, N Muna, K Mutia, P A Iffanolida, A Bowolaksono, R Muharam, A Hestiantoro |
| 6 | Absence of a correlation between intra-follicular androgen and AMH levels and the oocyte count in poor responder patients undergoing in vitro fertilization | Journal of Physics: Conference Series | 2018 | K Mutia, N Muna, N M D Suratih, R R Febri, O Riayati, R Muharam, A Hestiantoro, P A Iffanolida, B Wiweko |
| 7 | DNA methylation of the progesterone receptor B (PR-B) gene promoter in human eutopic endometrium, ectopic peritoneum, and ovarian endometriosis | Journal of Physics: Conference Series | 2018 | Darmawi, M L S Marwali, R R Febri, R Muharam, A Hestiantoro, and Asmarinah |
| 8 | Late embryo cleavage as an indicator of chromosome aneuploidy by pre-implantation genetic screening | Journal of Physics: Conference Series | 2018 | P A Iffanolida, B Wiweko, T Yuningsih, E Mansyur, N Muna, K Mutia, O Riayati, R Febri, and A Hestiantoro |
| 9 | Correlation between follicular fluid AMH levels and numbers of oocytes in polycystic ovarian syndrome patients undergoing in vitro fertilization | Journal of Physics: Conference Series | 2018 | B Wiweko, N Hanifah, A M Sholihah, S Wibawa, P A Iffanolida, A Hestiantoro |
| 10 | Gene expression of follicle-stimulating hormone receptors in granulosa cells in poor ovarian responders | Journal of Physics: Conference Series | 2018 | P A Iffanolida, B Wiweko, N Muna, N Hanifah, K Mutia, O Riayati, R R Febri, A Hestiantoro |
| 11 | DNA methylation of the androgen receptor gene promoter in the granulosa cells of polycystic ovary syndrome patients | Journal of Physics: Conference Series | 2018 | Desmawati, Ririn Rahmala Febri, Andon Hestiantoro, Asmarinah |
| 12 | BAX/BCL-2 expression in granulosa cells was not altered in patients with polycystic ovary syndrome | Journal of Physics: Conference Series | 2018 | R R Febri, B Wiweko, N Hanifah, A M Sholihah, P A Iffanolida, K Mutia, N Muna, O Riayati, A Hestiantoro |
Research Project in 5 Years
| No | Title | Years |
|---|---|---|
| 1 | Improving endometriosis awareness and diagnosis in Indonesia: increasing early detection with big data and artificial intelligence | 2024 |
| No | Title | Years |
|---|---|---|
| 1 | Hubungan Antara Resistensi Insulin, Komposisi Massa Tubuh, Leptin, dan adiponektin dengan Rasio LH:FSH pada Perempuan dengan Sindrom Ovarium Polikistik (SOPK) | 2023 |
| 2 | Hubungan Antara Resistensi Insulin, Komposisi Massa Tubuh, Leptin, dan adiponektin dengan Rasio LH:FSH pada Perempuan dengan Sindrom Ovarium Polikistik (SOPK) | 2023 |
| 3 | Kajian Sumber dan Mekanisme Pelepasan DNA Bebas Embrio dalam Medium Kultur Sebagai Upaya Pengembangan Seleksi Genetik Embrio Non-Invasif pada Program FertilisasiIn-Vitro | 2023 |
| 4 | Kajian Respon Makrofag terhadap LDL (Low Density Lipid) Teroksidasi pada Inflamasi Kronik Derajat Rendah Sindrom Ovarium Polikistik Obesitas dan non-Obesitas | 2023 |
| 5 | Hubungan antara polimorfisme gen hormone LHb, FSHb, dan FTO dengan Sindroma Ovarium Polikistik (SOPK) | 2023 |
| 6 | Korelasi Ekspresi miRNA let-7A-1 dan miRNA let-7F-1 dengan IL-6, IL-* dan VEGF A pada pasien Endometriosis | 2023 |
| 7 | Korelasi Inflamasi Kronis Tingkat Rendah dengan Resistensi Insulin pada SOPK Obesitas dan Non-obesitas | 2023 |
| 8 | Efek Acalypha indica Linn Terhadap Ekspresi PPAR Gamma dan Histopatologi Jaringan Adiposa Tersimpan Tikus Sprague Dawley Jantan yang Mengalami Obesitas | 2023 |
| No | Title | Years |
|---|---|---|
| 1 | Pengaruh Pemberian Dehydroepiandrosterone (DHEA) dan Koenzim Q10 (CoQ10) pada Model Hewan Coba Tikus Perespon Buruk Terhadap Respon Stimulasi Ovarium | 2022 |
| 2 | Efek PRP Terhadap Pemulihan Fungsi Ovarium pada Kasus POI Melalui Jalur PI3K/AKT/FOXO3 Serta Potensi Aktivasi Oogonial Stemcell | 2022 |
| 3 | Modifikasi Epigenetik Gen KISS1 pada Wanita dengan Sindrom Ovarium Polikistik (SOPK) di Indonesia Sebagai Dasar Terapi berbasis Etiologi | 2022 |
| 4 | Analisis Metilasi Gen Insulin pada Pasien Sindrom Ovarium Polikistik (SOPK) Nir-Obese dan Korelasinya dengan Ekspresi Gen Insulin Reseptor | 2022 |
| 5 | Kajian Sumber dan Mekanisme Pelepasan DNA Bebas Embrio dalam Medium Kultur Sebagai Upaya Pengembangan Seleksi Genetik Embrio Non-Invasif pada Program FertilisasiIn-Vitro | 2022 |
| 6 | Korelasi Inflamasi Kronis Tingkat Rendah dengan Resistensi Insulin pada Wanita Sindrom Ovarium Polikistik Obesitas dan Non-Obesitas | 2022 |
| 7 | Analisis Patogenesis Adenomiosis Terkait Transisi Mesenkim Epitel Melalui Jalur Persinyalan Notch: Perubahan Metilasi dan Ekspresi Gen NOTCH1 dan Pengaruhnya Terhadap Ekspresi Reseptor Progesteron | 2022 |
| 8 | Comparison of Ovarian Response and in vitro Fertilization Outcomes between Lean and Obese PCOS Patients | 2022 |
| 9 | Perubahan Struktur Pinopod dan Ekspresi Protein Integral pada Epitel Luminal Endometrium Tikus Setelah Pemberian FSH Rekombinan | 2022 |
| 10 | Transformasi Digital Sistem Kesehatan yang Berperspektif Luas: Dasar Pembangunan Ulang Arsitektur Kesehatan Global | 2022 |
| 11 | Pre-Implantation and Pre-natal Genetic Tests in Indonesia: Technical, Biological and Social Approach Update for a Developing Country | 2022 |
| 12 | Penelitian Multi Senter Perawatan Endometriosis yang Berpusat pada Pasien di Rumah Sakit - Rumah Sakit Rujukan dan Faktor-Faktor yang Mempengaruhi | 2022 |
| 13 | Sikap, Pengetahuan, dan Perilaku Terhadap Penerimaan Vaksin COVID-19 Pada Wanita dengan Infertilitas | 2022 |
| 14 | Tingkat Pengetahuan, Sikap, Kesadaran, dan Penerimaan Terhadap Preservasi Fungsi Fertilitas pada Perempuan dengan Endometriosis | 2022 |
| 15 | Pendekatan Berbasis Network Pharmacology Aktivasi Folikel Primordial: Nilai Prediksi Berbasis Interaksi Protein | 2022 |
| 16 | Pengaruh Paclitaxel Sebagai Terapi Kanker Terhadap Pertumbuhan dan Perkembangan Folikel Ovarium Mencit In Vitro | 2022 |
| 17 | Profil Panel Microrna (Mirna) sebagai Kandidat Diagnosis Dini Adenomyosis | 2022 |
| 18 | Model Prediksi Status Kromosom Embrio Berbasis Kecerdasan Buatan dengan Menggunakan Penilaian Morfologi dan Morfokinetik, Sekresi Micro RNA 372, Micro RNA 191, dan Cell Free DNA pada Medium Kultur Embrio | 2022 |
| No | Title | Years |
|---|---|---|
| 1 | Autofagi pada endometrium | 2020 |
| 2 | Propolis sebagai anti endometriosis | 2020 |
| 3 | Profil demografi, status gizi dan infeksi chlamydia pada pasangan calon pengantin di DKI Jakarta | 2020 |
| 4 | Autophagy-Related-Gene (ATG) on endometriosis | 2020 |
| 5 | Natural Killer (NK) cells as potential targets for immunological therapy in women with endometriosis | 2020 |
| 6 | microRNA-83 and microRNA-193 as candidate biomarker for endometriosis | 2020 |
| 7 | Correlation between FTO gene methylation and PCOS | 2020 |
| 8 | Comparison of the Umbilical Cord Blood’s Androgen Level and Gene Expressions in the Newborns of Mothers with Polycystic Ovary Syndrome (PCOS) and Healthy Mothers | 2020 |
| 9 | Association Between Luteinizing Hormone Beta Subunit and Testosterone Index in Polycystic Ovary Syndrome Patients | 2020 |
| No | Title | Years |
|---|---|---|
| 1 | Pengaruh mikronutrien dan polimorfisme gen IRS-1, VDR dan FTO dalam berbagai fenotip subjek SOPK | 2019 |
| 2 | MicroRNA sebagai biomarker non invasif untuk implantasi embrio | 2019 |
| 3 | Studi morfologi dan perkembangan blastokista terhadap kejadian aneuploidi dan mosaik | 2019 |
| 4 | Studi ekspresi miRNA pada pasien dengan gangguan kesuburan: Biomarker potensial untuk keberhasilan fertilisasi in vitro | 2019 |
| 5 | Hubungan kadar zinc dan kalsium dalam serum dan cairan folikel dengan ekspresi GDF-9 terhadap maturasi oosit | 2019 |
| 6 | Ekspresi miRNA pada endometrium fase jendela implantasi pasien infertilitas: Kaitannya dengan ekspresi mRNA gen homeobox 10 | 2019 |
| 7 | Regenerasi selaput amnion dan gel fibrin menjadi organ kulit melalui pengembangan kultur sistim keratinosit dan sel punca pengganti kulit hilang | 2019 |
| 8 | Rekayasa Dinding Jantung Artifisial: Kultur Mesenchymal Stem Cells (MSC) dengan Bioreaktor Stimulasi Mekanik | 2019 |
| 9 | Pengembangan Teknik Terapi Infark Miokard menggunakan Scaffold yang telah Dikultur dengan Kardiomiosit dan Mesenchymal Stem Cell (MSC) secara In Vitro | 2019 |
| 10 | CD107a sebagai marker sel NK di endometriosis | 2019 |
| No | Title | Years |
|---|---|---|
| 1 | Profil mRNA gen FTO, IRS-1, dan VDR ppada Pasien Sindrom Ovarium Polikistik (SOPK) dengan Obesitas dan nir-Obesitas: Studi terkait Sistem Metabolisme Tubuh | 2018 |
| 2 | Hubungan antara Metilasi DNA dan Kadar SHBG pada Pasien SOPK nir-obese | 2018 |
| 3 | Korelasi Kadar Trigliserida dengan Free Testosterone Index dan Skor Ferimann Gallway pada Pasien SOPK | 2018 |
| 4 | Faktor-faktor yang Mempengaruhi Resistensi Insulin pada Pasien SOPK | 2018 |
| 5 | Hubungan Hubungan Kadar Kisspeptin-54 dan Kadar Human Chorionic Gonadotropin (hCG) Pituitari dengan Gangguan Kognitif Minimal pada Perempuan Pascamenopause | 2018 |
| 6 | Korelasi Kadar Kisspeptin dan Rasio FSH/estradiol dengan Gangguan Kognitif Minimal pada Perempuan Pascamenopause | 2018 |
| 7 | Korelasi Kadar Human Chorionic Gonadotropin (hCG) dan Rasio FSH/estradiol dengan Gangguan Kognitif Minimal pada Perempuan Pascamenopause | 2018 |
| 8 | Nisbah Myo-inositol (MI) dan D-Chiro-inositol (DCI) Cairan Folikel Sebagai Penentu Fertilisasi Oosit Pasien Sindrom Ovarium Polikistik Peserta Program Fertilisasi Invitro | 2018 |
| 9 | Korelasi Nisbah Myo-inositol (MI) dan D-Chiro-inositol (DCI) Cairan Folikel dengan Maturasi Oosit pada Pasien SOPK Peserta Program FIV | 2018 |
| 10 | Korelasi Nisbah Myo-inositol (MI) dan D-Chiro-inositol (DCI) Cairan Folikel dengan Dosis Gonadotropin yang digunakan pada Pasien SOPK Peserta Program FIV | 2018 |
| 11 | Penilaian Kualitas Pelayanan Berdasarkan Harapan dan Persepsi Pasien dengan Model SERVQUAL di Klinik Bayi Tabung Yasmin RSCM Kencana | 2018 |
| 12 | Korelasi Kadar HCG Serum dan Ekspresi Messenger RNA Reseptor Luteininzing Hormon Sel Granulosa terhadap Maturasi Oosit | 2018 |
| 13 | Korelasi kadar HCG serum dan maturitas oosit | 2018 |
| 14 | Korelasi antara Morfologi dan Perkembangan Embrio dengan Status Kromosom | 2018 |
| 15 | Korelasi antara Indeks Fragmentasi DNA dengan Status Kromosom | 2018 |
| 17 | Korelasi antara lama waktu pembentukan pronukleus dengan status kromosom | 2018 |
Collaboration
| No | Name of Collaboration | Year | Collaborator (International/National) |
|---|---|---|---|
| 1 | Togas Tolandi | 2022 | International |
| 2 | Evelyn Telfer | 2022 | International |
| 3 | Hang Wu Raymond Li | 2022 | International |
| 4 | Mulyoto Pengestu | 2022 | International |
| No | Name of Collaboration | Year | Collaborator (International/National) |
|---|---|---|---|
| 1 | Prof. Yutaka Osuga, The University of Tokyo, Japan | 2020 | International |
| 2 | Prof. Hiroaki Funahashi, Okayama University, Japan | 2020 | International |
| 3 | Prof. Norihiro Sugino, Graduate School of Medicine, Yamaguchi University, Japan | 2020 | International |
| 4 | Richard Anderson | 2020 | International |
| 5 | Evelyn Telfer | 2020 | International |
| 6 | Nao Suzuki | 2020 | International |
| 7 | Collin Duncan | 2020 | International |
| 8 | Mick T. Rae | 2020 | International |
| 9 | Mulyoto Pangestu | 2020 | International |
| 10 | Ade Jamal, Universitas Al Azhar Indonesia, Jakarta, Indonesia | 2020 | National |
| 11 | Ali Akbar Septiandri, Universitas Al Azhar Indonesia, Jakarta, Indonesia | 2020 | National |
| 12 | FMIPA | 2020 | National |
Organization
Prof. Dr. dr. Andon Hestiantoro, SpOG(K), MPH
Dr. dr. Kanadi Sumapraja, SpOG(K), MSc
Dr. dr. Achmad Kemal Harzif, SpOG(K)
Prof. Dr. dr. R Muharam, SpOG(K), MPH
Dr. dr. Gita Pratama, SpOG(K), MRepSc
dr. Vita Silvana, SpOG(K)
Prof. Dr. dr. Budi Wiweko, SpOG(K), MPH
dr. Mila Maidarti, SpOG(K), PhD
Irwina Eka Deraya, S.Si., M.Biomed
Kresna Mutia, M.Si
Pritta Ameilia Iffanolida, S.Si, M.Biomed
Naylah Muna, S.Si
Ririn Rahmala Febri, SKM., M.Biomed
