Human Nutrition

The Human Nutrition Research Center at IMERI, Faculty of Medicine Universitas Indonesia, is dedicated to advancing scientific knowledge in human nutrition to improve health across the life course. The cluster focuses on five key research areas:
1. Early Life and Child Nutrition for Optimal Growth and Development
2. Dietary Quality, Gut Microbiota, and Epigenetics
3. Healthy Lifestyle for Wellness and the Prevention of Obesity and NCDs
4. Healthy Aging and Nutrition for a Better Quality of Life
5. Sustainable Food Systems and Public Health Nutrition.

Publication

No	Title	Name and link of the Journal	Year	Authors
1	Serum Hemoglobin Level, Anemia, and Growth Were Unaffected by a 12-Month Multiple-Micronutrient Powder Intervention Among Children Aged 8–10 Months in a Low-Socioeconomic-Status Community of Jakarta	Nutrients https://doi.org/10.3390/nu17152520"	31 July 2025	Dian Novita Chandra, Saptawati Bardosono, Tonny Sundjaya, Tjhin Wiguna, and Rini Sekartini
2	Protocol for a randomized controlled trial to evaluate the impact of daily supplementation with zinc, chromium, vitamin C, and copper on progression of prediabetes in Jakarta, Indonesia	Contemporary Clinical Trials https://doi.org/10.1016/j.cct.2025.108007"	11 July 2025	Rina Agustina, Erfi Prafiantini, Alfi R. Putri, Rachmi Mufida, Hanifa Hanifa, Shofura Afifah, Dicky L. Tahapary, Anuraj H. Shankar, Pradana Soewondo
3	Usability testing of EatsUp®: mobile application for monitoring balanced dietary practices and active lifestyle among adolescents—a study in Jakarta, Indonesia	Frontiers in Digital Health https://doi.org/10.3389/fdgth.2025.1506952	13 June 2025	Erfi Prafiantini, Rina Agustina, Betty Purwandari, Dian Novita Chandra, Dini Rahma Bintari, Fellatinnisa Zafira Rajwadini, Jihan Farhanah and Aryono Hendarto
4	Role of oral probiotic supplementation on gut permeability in obesity: A systematic review of randomized controlled trials	Food Hydrocolloids for Health https://doi.org/10.1016/j.fhfh.2025.100225	6 June 2025	Alpha Fardah Athiyyah, Triska Susila Nindya, Reza Gunadi Ranuh, Andy Darma, Khadijah Rizky Sumitro, Purwo Sri Rejeki, Lilik Djuari, Subijanto Marto Sudarmo, Rina Agustina
5	Effect of prenatal multiple micronutrient supplementation compared with iron and folic acid supplementation on size at birth and subsequent growth through 24 mo of age: a systematic review and meta-analysis	The American Journal of Clinical Nutrition https://doi.org/10.1016/j.ajcnut.2025.04.022	28 April 2025	Filomena Gomes, Seth Adu-Afarwuah, Rina Agustina, Hasmot Ali, Amrita Arcot,Shams Arifeen, Charles D Arnold, Robert E Black, Parul Christian, Kathryn G Dewey, Wafaie W Fawzi, Lotta Hallamaa, John Hoddinott, Mihaela C Kissell, Klaus Kraemer, Carl Lachat, Sophie E Moore, Kenneth Maleta, Carolina Pereira, Dominique Roberfroid, Saijuddin Shaikh, Anuraj H Shankar, Emily R Smith, Inan Subarkah, Rahardjo Sunawang, Dongqing Wang, Lee S-F Wu, Martin N Mwangi
6	Study protocol for a randomised controlled trial evaluating the efficacy of dietary modulation of probiotics on nutritional status and antibody response to SARS-CoV-2 in Indonesian adolescents: gut-lung axis (DIVINE)	BMJ Open https://doi.org/10.1136/bmjopen-2024-087934	2 April 2025	Rina Agustina, Karina R. Ekawidyani, Mira Mutiyani, Erfi Prafiantini, Triska S. Nindya, Wahyu Damayanti, Purwo S. Rejeki, Lilik Djuari, Emy Huriyati, Julie E. Bines, Muhammad Juffrie
7	Nutrient Intake Adequacy among Adults in Indonesia and Malaysia: A Systematic Review and Meta-Analysis	Current Developments in Nutrition https://doi.org/10.1016/j.cdnut.2025.106010	24 March 2015	Rina Agustina, Rachmi Mufida, Wanda Lasepa, Ajeng Mustika, Ardini Debilauralita, Sepriani T Limbong, Deviana AS Siregar, Erfi Prafiantini, Nurul RM Manikam, Pradana Soewondo
8	Association of Prepregnancy Body Mass Index with Gut Microbiota Diversity and Abundance in Pregnant Women	The Journal of Nutrition https://doi.org/10.1016/j.tjnut.2025.02.006	14 February 2025	Maria Erlin, Davrina Rianda, Fadilah Fadilah, Linda Erlina, Mega Diasty Rahayu, Erfi Prafiantini, Ali Sungkar, Anuraj H Shankar, Rina Agustina
9	The Effect of Probiotics and Calcium Supplementation During Childhood on Hemoglobin Level and Anemia Prevalence: A 10-Year Follow-Up Study	Current Developments in Nutrition https://doi.org/10.1016/j.cdnut.2024.103485	29 June 2024	Davrina Rianda, Rina Agustina
10	Malnutrition Prevalence and Nutrient Intakes of Indonesian Older Adults in Institutionalized Care Setting: A Systematic Review of Observational Studies	Annals of Nutrition and Metabolism https://doi.org/10.1159/000538790	18 April 2024	Esthika Dewiasty, Siti Setiati, Rina Agustina, Siti Rizny F. Saldi, Nove Zain Wisuda, Arvin Pramudita, Meutia Kumaheri, Gracia Fensynthia, Fariza Rahmah, Reganedgary Jonlean, Lisette C.P.G.M. de Groot
11	Cooking behavior among mothers of children aged 2-5 years old in Kendari, Southeast Sulawesi, Indonesia	BMC Public Health https://doi.org/10.1186/s12889-024-17826-1	6 February 2024	Intan R Nirmala, Judhiastuty Februhartanty, Rina Agustina, Rini Sekartini
12	The impact of government pandemic policies on the vulnerability of healthcare workers to SARS-CoV-2 infection and mortality in Jakarta Province, Indonesia	Annals of Medicine https://doi.org/10.1080/07853890.2023.2293306	11 January 2024	Rina Agustina, Davrina Rianda, Aly Lamuri, Karina Rahmadia Ekawidyani, Deviana Ayushinta Sani Siregar, Dyana Santika Sari, Prashti Mutia Wulan, Natasha Dianasari Devana, Ari Fahrial Syam, Ahmad Jabir Rahyussalim, Dwi Oktavia Handayani, Widyastuti Widyastuti, Anuraj Harish Shankar, Ngabila Salama
13	Behavioural and environmental risk factors associated with primary schoolchildren’s overweight and obesity in urban Indonesia	Public Health Nutrition https://doi.org/10.1017/S1368980023000897	4 Agustus 2023	Margarita de Vries Mecheva, Matthias Rieger, Robert Sparrow, Erfi Prafiantini, Rina Agustina
14	Nutrient intakes of pregnant and lactating women in Indonesia and Malaysia: Systematic review and meta-analysis	Frontiers in Nutrition https://doi.org/10.3389/fnut.2023.1030343	30 March 2023	Rina Agustina, Davrina Rianda, Wanda Lasepa, Fitya S. Birahmatika, Vladimir Stajic and Rachmi Mufida
15	Development and preliminary validity of an Indonesian mobile application for a balanced and sustainable diet for obesity management	BMC Public Health https://doi.org/10.1186/s12889-022-13579-x	20 June 2022	Rina Agustina, Eka Febriyanti, Melyarna Putri, Meriza Martineta, Novi S Hardiany, Dyah E Mustikawati, Hanifa Hanifa, Anuraj H Shankar
16	Long-term benefits of probiotics and calcium supplementation during childhood, and other biomedical and socioenvironmental factors, on adolescent neurodevelopmental outcomes	Journal of Functional Foods https://doi.org/10.1016/j.jff.2022.105014	3 March 2022	Davrina Rianda, Sri Hartati R. Suradijono, Evania A. Setiawan, Fenny Susanto, Meilianawati Meilianawati, Erfi Prafiantini, Frans J. Kok, Anuraj H. Shankar, Rina Agustina
17	Association between Dietary Inflammatory Index and Serum Tumor Necrosis Factor Alpha Level in Adult with Normal and Obese Body Mass Index in Jakarta	International Journal of Innovative Science and Research Technology	November 2021	Lidya Yudith Priskila, Rina Agustina, Ratna Djuwita, Inge Permadhi, Fiastuti Witjaksono, Murdani Abdullah, Erfi Prafiantini
18	Relationships of Child-, Parents-, and Environment-Associated Determinants with Diet Quality, Physical Activity, and Smoking Habits Among Indonesian Urban Adolescents	Food and Nutrition Bulletin https://doi.org/10.1177/03795721211046145	21 October 2021	Rina Agustina, Davrina Rianda, Evania Astella Setiawan
19	Integration of symptomatic, demographical and diet-related comorbidities data with SARS-CoV-2 antibody rapid diagnostic tests during epidemiological surveillance: a cross-sectional study in Jakarta, Indonesia	BMJ Open https://doi.org/10.1136/bmjopen-2020-047763	10 August 2021	Rina Agustina, Ari Fahrial Syam, Fadila Wirawan, Indah S Widyahening, Ahmad Jabir Rahyussalim, Yusra Yusra, Davrina Rianda, Erlina Burhan, Ngabila Salama, Rebekka Daulay, Ahmad Rhyza Vertando Halim, Anuraj H Shankar
20	Adolescent Nutrition—Developing a Research Agenda for the Second Window of Opportunity in Indonesia	Food and Nutrition Bulletin https://doi.org/10.1177/0379572120983668	20 July 2021	Robert Sparrow, Rina Agustina, Hilde Bras, Grace Sheila, Matthias Rieger, Athia Yumna, Edith Feskens, and Alida Melse-Boonstra
21	Associations of Knowledge, Attitude, and Practices toward Anemia with Anemia Prevalence and Height-for-Age Z-Score among Indonesian Adolescent Girls	Food and Nutrition Bulletin https://doi.org/10.1177/03795721211011136	20 July 2021	Rina Agustina, Fadila Wirawan, Arini A Sadariskar, Ainanur A Setianingsing, Khairun Nadiya, Erfi Prafiantini, Eriana K Asri, Tutut S Purwanti, Sri Kusyuniati, Elvina Karyadi, Manoj K Raut
22	Psychosocial, Eating Behavior, and Lifestyle Factors Influencing Overweight and Obesity in Adolescents	Food and Nutrition Bulletin https://doi.org/10.1177/0379572121992750	20 July 2021	Rina Agustina, Meilianawati, Fenny, Atmarita, Suparmi , Kun A Susiloretni, Wiji Lestari, Kirana Pritasari, Anuraj H Shankar
23	The Triple Burden of Malnutrition Among Adolescents in Indonesia	Food and Nutrition Bulletin https://doi.org/10.1177/03795721211007114	20 July 2021	Jee Hyun Rah, Alida Melse-Boonstra, Rina Agustina, Kesso Gabrielle van Zutphen, Klaus Kraemer
24	Snacks, nudges and asymmetric peer influence: Evidence from food choice experiments with children in Indonesia	Journal of Health Economics https://doi.org/10.1016/j.jhealeco.2021.102508	18 July 2021	Margarita de Vries Mecheva, Matthias Rieger, Robert Sparrow, Erfi Prafiantini, Rina Agustina
25	Tenth year reenrolment randomized trial investigating the effects of childhood probiotics and calcium supplementation on height and weight at adolescence	Scientific Reports https://doi.org/10.1038/s41598-021-88819-y	4 June 2021	Evania Astella Setiawan, Davrina Rianda, Muzal Kadim, Meilianawati, Fenny Susanto, Frans J Kok, Anuraj H Shankar, Rina Agustina
26	Prevalence of lactose intolerance and nutrients intake in an older population regarded as lactase non-persistent	Clinical Nutrition ESPEN https://doi.org/10.1016/j.clnesp.2021.03.033	10 April 2021	Esthika Dewiasty, Siti Setiati, Rina Agustina, Arya Govinda Roosheroe, Murdani Abdullah, Rahmi Istanti, Lisette CPGM de Groot
27	Associations of maternal diet quality with weight gain during pregnancy and obesity at three-year postpartum in Jakarta	PLOS ONE https://doi.org/10.1371/journal.pone.0244449	31 December 2020	Lestari Octavia, Rina Agustina, Arindah Nur Sartika, Annisa Dwi Utami, Yayang Aditia Dewi, Anastasia Hayuningtyas, Mutia Winanda, Erfi Prafiantini, Asmarinah
28	Associations between diet quality, blood pressure, and glucose levels among pregnant women in the Asian megacity of Jakarta	PLOS ONE https://doi.org/10.1371/journal.pone.0242150	25 November 2020	Deviana A. S. Siregar, Davrina Rianda, Rima Irwinda, Annisa Dwi Utami, Hanifa Hanifa, Anuraj H. Shankar, Rina Agustina
29	Associations of meal patterning, dietary quality and diversity with anemia and overweight-obesity among Indonesian school-going adolescent girls in West Java	PLOS ONE https://doi.org/10.1371/journal.pone.0231519	23 April 2020	Rina Agustina, Khairun Nadiya, El A Andini, Ainanur A Setianingsih, Arini A Sadariskar, Erfi Prafiantini, Fadila Wirawan, Elvina Karyadi, Manoj K Raut
30	Consumption patterns of sweetened condensed milk in the diet of young Indonesian children and its potential nutritional health consequences	Asia Pacific Journal of Clinical Nutrition https://doi.org/10.6133/apjcn.202003_29(1).0003	1 March 2020	Mohammad Juffrie, Ratu Ayu Dewi Sartika, Roy Alexander Sparringa, Lindawati Wibowo, Widjaja Lukito
31	Intersectoral and eco-nutritional approaches to resolve persistent anemia in Indonesia	Asia Pacific Journal of Clinical Nutrition https://doi.org/10.6133/apjcn.202012_29(s1).01	2020	Widjaja Lukito, Mark L Wahlqvist
32	Dietary and Plasma Carboxymethyl Lysine and Tumor Necrosis Factor-α as Mediators of Body Mass Index and Waist Circumference among Women in Indonesia	Nutrients https://doi.org/10.3390/nu11123057	14 December 2019	Patricia Budihartanti Liman, Rina Agustina, Ratna Djuwita, Jahja Umar, Inge Permadhi, Helmizar, Adi Hidayat, Edith J M Feskens, Murdani Abdullah
33	Food in the Anthropocene: the EAT–Lancet Commission on healthy diets from sustainable food systems	The Lancet https://doi.org/10.1016/S0140-6736(18)31788-4	2 - 8 February 2019	Walter Willett, Johan Rockström, Brent Loken, Marco Springmann, Tim Lang, Sonja Vermeulen, Tara Garnett, David Tilman, Fabrice DeClerck, Amanda Wood, Malin Jonell, Michael Clark, Line J Gordon, Jessica Fanzo, Corinna Hawkes, Rami Zurayk, Juan A Rivera, Wim De Vries, Lindiwe Majele Sibanda, Ashkan Afshin, Abhishek Chaudhary, Mario Herrero, Rina Agustina, Francesco Branca, Anna Lartey, Shenggen Fan, Beatrice Crona, Elizabeth Fox, Victoria Bignet, Max Troell, Therese Lindahl, Sudhvir Singh, Sarah E Cornell, K Srinath Reddy, Sunita Narain, Sania Nishtar, Christopher J L Murray
34	Formative research on development of semi-quantitative food frequency questionnaire for selected multi ethnic foods in Jakarta	Journal of International Dental and Medical Research https://www.jidmr.com/journal/wp-content/uploads/2019/04/45-M19329-ED-Rina-Agustina-M-2.pdf	1 January 2019	Rina Agustina, Gabriela Widyakarin Tjandra, Nurul Hasanah, Lidya Yudith Priskila, Ayu Diandra Sari, Fitriana Nugraheni, Arini Ayatika Sadariskar, Okky Lupita, Murdani Abdullah, Ratna Djuwita, Inge Permadhi, Erfi Prafiantini
35	Maternal contributors to intergenerational nutrition, health, and well-being: revisiting the Tanjungsari Cohort Study for effective policy and action in Indonesia	Asia Pacific Journal of Clinical Nutrition https://doi.org/10.6133/apjcn.201901_28(s1).0001	2019	Widjaja Lukito, Lindawati Wibowo, Mark L Wahlqvist
36	The Clinical Nutrition Research Agenda in Indonesia and beyond: ecological strategy for food in health care delivery	Asia Pacific Journal of Clinical Nutrition https://doi.org/10.6133/apjcn.062017.s12	6 June 2017	Widjaja Lukito, Lindawati Wibowo, Mark L Wahlqvist, and the Scientific Advisory Group

Current Research

Hubungan Pola Makan dan Kadar Seng Rambut terhadap Komposisi Tubuh, TNF-a, dan Tekanan Darah pada Wanita Usia Subur Suku Minangkabau, Sunda, Jawa, Betawi, dan Cina di Jakarta.

Collaboration

Blackmores
University of California, Davis.
Departement of Nutrition, Faculty of Medicine, Universitas Indonesia
The EAT-Lancet Commission.
Sanofi.
OUCRU

Facilities

The BOD POD is the world’s only Air Displacement Plethysmography (ADP) system using whole body densitometric principles to determine body composition (Fat and Fat-Free Mass) and Thoracic Gas Volume in adults and children.

BIA SECA® mBCA 515 is a validated method to measure the difference in electrical conductivity between the body’s muscle and fat tissue. The 4-compartment measurement includes fat-free mass, skeletal muscle mass, a body composition chart, phase angle, and body water percentage.

BIA Tanita® MC780 is a 4-compartment measurement system that uses advanced bioelectrical impedance analysis technology to provide highly accurate calculations of fat mass, lean mass (muscle), bone mineral density, and total body water.